Table 1.
Clinical and demographic characteristics of the study population (n = 190).
| Women (n = 88) | Men (n = 102) | P | |
|---|---|---|---|
| Median age, years (IQR) | 41.5 (27.2-52.7) | 45 (30.7-58.2) | 0.232 |
| Disease type | |||
| CD | 53 (60.2) | 47 (46.1) | |
| UC | 35 (39.8) | 55 (53.9) | 0.051 |
| Disease duration, months (IQR) | 4.4 (3.1-5.9) | 4.5 (3.2-5.9) | 0.757 |
| Median BMI, kg/m2 (IQR) | 22.7 (20.1-26.1) | 25.1 (22.4-28.2) | 0.001* |
| Tobacco use | |||
| Smoker | 20 (22.7) | 18 (17.6) | 0.031* |
| Former smoker | 25 (28.4) | 48 (47.1) | |
| Non-smoker | 43 (48.9) | 36 (35.3) | |
| Marital status | |||
| Married/partner | 51 (58) | 60 (58.8) | 0.904 |
| Single/divorced/widowed | 37 (42) | 42 (41.2) | |
| Education | |||
| Low level | 62 (70.5) | 71 (69.6) | 0.899 |
| High level | 26 (29.5) | 31 (30.4) | |
| Active employment | 38 (43.2) | 61 (59.8) | 0.022* |
| Comorbidity | 43 (48.9) | 41 (40.2) | 0.230 |
| Previous history of MAD | 16 (18.2) | 2 (2) | < 0.001* |
| CD Montreal classification | |||
| Age group | |||
| A2: 17–40 years | 24 (45.3) | 24 (51.1) | 0.564 |
| A3: ≥40 years | 29 (54.7) | 23 (48.9) | |
| Location of Crohn’s (>1 location possible) | |||
| L1: Ileal | 26 (49.1) | 29 (61.7) | 0.205 |
| L2: Colonic | 10 (18.9) | 5 (10.6) | 0.250 |
| L3: Ileocolonic | 17 (32.1) | 12 (25.5) | 0.472 |
| L4: Upper GI | 3 (5.7) | 3 (6.4) | 1 |
| Crohn’s behavior | |||
| B1: Inflammatory | 40 (75.5) | 35 (74.5) | 0.959 |
| B2: Stricturing | 8 (15.1) | 8 (17) | |
| B3: Penetrating | 5 (9.4) | 4 (8.5) | |
| Perianal involvement | 5 (9.4) | 2 (4.3) | 0.311 |
| UC Montreal classification | |||
| E1: Proctitis | 13 (37.1) | 11 (20) | 0.198 |
| E2: Left-sided colitis | 13 (37.1) | 25 (45.5) | |
| E3: Extensive colitis | 9 (25.7) | 19 (34.5) | |
| IBD activity | |||
| Mild | 40 (45.5) | 44 (43.1) | 0.748 |
| Moderate/severe | 48 (54.5) | 58 (56.9) | |
| Median CRP, mg/L (IQR) | 11 (2.4-58.8) | 6.6 (1.9-34.5) | 0.149 |
| Median fecal calprotectin, μg/g (IQR) | 602 (122-1994) | 532 (94.2-1320) | 0.422 |
| Anemia | 34 (38.6) | 25 (24.5) | 0.036* |
| EIM | 14 (15.9) | 7 (6.9) | 0.047* |
| Family history of IBD | 26 (29.5) | 16 (15.7) | 0.022* |
Values are n (%) unless otherwise noted. Abbreviations: CD, Crohn’s disease; UC, ulcerative colitis; IBD, inflammatory bowel disease; BMI, body mass index; MAD, mood and/or anxiety disorders; CRP, C-reactive protein; EIM, extra-intestinal manifestations; IQR, interquartile range.
*statistically significant at P < .05.