Formulation ratios of different components used in formulation of LNPs.
| Lipid nanoparticles | Dye (mole ratio) | DPPC (moles%) | DOPC (moles%) | DPPG (moles%) | PEG-2000-AMINE (moles%) | 5BDBD (mole ratio) |
|---|---|---|---|---|---|---|
| Lipo | 47 | 47 | 0.5 | 5.5 | ||
| Lipo + dye | 1 : 500 | 47 | 47 | 0.5 | 5.5 | |
| Lipo + 5BDBD | 47 | 47 | 0.5 | 5.5 | 1 : 100 | |
| Lipo + 5BDBD + dye | 1 : 500 | 47 | 47 | 0.5 | 5.5 | 1 : 100 |