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. 2023 Dec 5;3(12):e0001813. doi: 10.1371/journal.pgph.0001813

Table 3. Feasibility and acceptability of real-time adherence monitor.

(N = 58, i.e. 19 in the daily SMS arm, 20 in the weekly SMS arm, 19 in the control arm)
Feasibility issue Comments
Data loss* 342/9224 (3.7%) of data were lost because of technical issues with the adherence monitors.
Device malfunction* 2 (3%) out of 60 devices malfunctioned due to technical failures and were replaced.
Device battery changes*
Taking pills from another source
Reason(s) (n = 10)
•Was traveling
•Had not refilled the device
Openings without pill removal (n = 8)
•During refilling the monitor
•Opened accidently
Study staff replaced 4 batteries; poor mobile network resulted in repeated attempts to transmit the data which depleted the batteries before the anticipated battery lives.
10 (18%) of TB patients reported ever taking pills from another source during the study period.
7 (70%)
3 (30%)
4 (50%)
4 (50%)
Acceptability

Perceived usefulness
Perceived ease of use

58 (100%) of TB patients reported that the real-time monitor: a) was useful in their TB medication adherence; b) helped them take their medication in time/as prescribed; d) positively affected the way they felt about taking medicine; e) and made it easier for TB patients to take their medication.
58 (100%) of TB patients found the real-time monitor easy to open and close, and remember to get pills.
45 (78%) of TB patients found the real-time monitor easy to travel with.
Disclosure from the real-time monitor 3 (5%) of TB patients reported that the adherence monitor resulted in unwanted disclosure of their TB status

*Data about data loss, device malfunction, and battery changes were collected from Wisepill device. All other data were collected via patient questionnaires.