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. 2023 Dec 1;7(12):e0333. doi: 10.1097/HC9.0000000000000333

FIGURE 4.

FIGURE 4

DR persisted and predicted decreased native liver survival during follow-up. (A) DR%, (B) BE%, (C) PIH%, and (D) PIH density in patients with follow-up biopsies at KPE and during follow-up according to age [KPE (n = 116); 0–2 y (n = 55); 2–6 y (n = 37); 6–12 y (n = 32); >12 y (n = 17)] and subsequent LT or NL survival at latest follow-up, and Kaplan-Meier native liver survival curves according to optimal cut points calculated with receiver operator characteristics analyses. The median time from protocol follow-up biopsy to LT was 4.3 (2.4–6.6) years. Violin plots display median, interquartile range, and individual data points. The shaded areas of Kaplan-Meier curves represent 95% CI. Abbreviations: BE, biliary epithelium; DR, ductular reaction; KPE, Kasai portoenterostomy; LT, liver transplantation; NL, native liver; PIH, parenchymal intermediate hepatocyte.