Table 2. Comparison of clinical and laboratory characteristics, initial parameters of the InsulinAPP protocol and follow-up of individuals with type 2 diabetes who used basal-bolus, bolus-correction insulin therapy regimens and that required a change from the bolus-correction to basal-bolus regimen in the first ten days of the protocol.
Variable | Bolus-correction insulin regimen (n = 33) | Change from bolus-correction to basal-bolus (n = 40) | Basal-bolus insulin regimen (n = 69) | P | |
---|---|---|---|---|---|
Admission BG, mg/dL | 148.0 (72.0) | 199.5 (86.0) | 248.0 (130.5) | <0.001 † | |
HbA1c, % | 6.6% (1.5%) | 8.0% (2.8%) | 9.4% (4.2%) | <0.001 † | |
InsulinAPP protocol | |||||
BG measurements | 741 | 968 | 1484 | ||
BG measurements per individual | 22.5 | 24.2 | 21.5 | ||
Hypoglycemia episodes | 10 (1.3%) | 12 (1.2%) | 27 (1.8%) | ||
% hypoglycemia per individual | 0% (0.03%) | 0% (0%) | 0% (0.04%) | 0.586 † | |
BG episodes 70-180 mg/dL | 647 (87.3%) | 730 (75.4%) | 871 (58.7%) | ||
% BG 70-180 mg/dL | 93.3 (14.3) | 76.7 (23.5) | 65.0 (40.9) | <0.001 † | |
Follow-up | |||||
Hospital discharge | 28 (84.8%) | 38 (95.0%) | 63 (91.3%) | 0.310 * | |
Transfer to another ward | 6 (18.2%) | 3 (7.5%) | 10 (14.5%) | 0.428 ‡ | |
ICU transfer | 4 (12.1%) | 2 (5.0%) | 2 (2.9%) | 0.173 ‡ | |
Indication of palliative care | 2 (6.1%) | 1 (2.5%) | 3 (4.3%) | 0.757 ‡ | |
Deaths | 5 (15.2%) | 2 (5.0%) | 6 (8.7%) | 0.310 ‡ |
Data are median (interquartile range) or n (%).
Pearson’s chi-squared test.
Kruskal-Wallis rank-sum test.
Fisher’s exact test.
BG: blood glucose; ICU: intensive care unit.