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. 2022 Jun 27;66(4):498–505. doi: 10.20945/2359-3997000000496

Table 2. Comparison of clinical and laboratory characteristics, initial parameters of the InsulinAPP protocol and follow-up of individuals with type 2 diabetes who used basal-bolus, bolus-correction insulin therapy regimens and that required a change from the bolus-correction to basal-bolus regimen in the first ten days of the protocol.

Variable Bolus-correction insulin regimen (n = 33) Change from bolus-correction to basal-bolus (n = 40) Basal-bolus insulin regimen (n = 69) P
Admission BG, mg/dL 148.0 (72.0) 199.5 (86.0) 248.0 (130.5) <0.001
HbA1c, % 6.6% (1.5%) 8.0% (2.8%) 9.4% (4.2%) <0.001
InsulinAPP protocol
BG measurements 741 968 1484
BG measurements per individual 22.5 24.2 21.5
Hypoglycemia episodes 10 (1.3%) 12 (1.2%) 27 (1.8%)
% hypoglycemia per individual 0% (0.03%) 0% (0%) 0% (0.04%) 0.586
BG episodes 70-180 mg/dL 647 (87.3%) 730 (75.4%) 871 (58.7%)
% BG 70-180 mg/dL 93.3 (14.3) 76.7 (23.5) 65.0 (40.9) <0.001
Follow-up
Hospital discharge 28 (84.8%) 38 (95.0%) 63 (91.3%) 0.310 *
Transfer to another ward 6 (18.2%) 3 (7.5%) 10 (14.5%) 0.428
ICU transfer 4 (12.1%) 2 (5.0%) 2 (2.9%) 0.173
Indication of palliative care 2 (6.1%) 1 (2.5%) 3 (4.3%) 0.757
Deaths 5 (15.2%) 2 (5.0%) 6 (8.7%) 0.310

Data are median (interquartile range) or n (%).

*

Pearson’s chi-squared test.

Kruskal-Wallis rank-sum test.

Fisher’s exact test.

BG: blood glucose; ICU: intensive care unit.