Table 1.
Baseline characteristics of study participants
| Characteristic | Overall, N = 3071 |
AML, N = 2241 |
B-cell ALL, N = 491 |
MPAL, N = 151 |
T-cell ALL, N = 181 |
Ambiguous lineage, N = 11 |
|---|---|---|---|---|---|---|
| Age | 58 (46, 66) | 60 (51, 67) | 55 (40, 63) | 55 (42, 63) | 38 (30, 54) | 27 (27, 27) |
| Age ≥ 65 | 88 (29%) | 77 (34%) | 8 (16%) | 2 (13%) | 1 (5.6%) | 0 (0%) |
| Age ≥ 70 | 46 (15%) | 44 (20%) | 2 (4.1%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Sex | ||||||
| Female | 127 (41%) | 102 (46%) | 16 (33%) | 5 (33%) | 4 (22%) | 0 (0%) |
| Male | 180 (59%) | 122 (54%) | 33 (67%) | 10 (67%) | 14 (78%) | 1 (100%) |
| Broad Ancestry | ||||||
| European | 184 (60%) | 133 (59%) | 32 (65%) | 9 (60%) | 9 (50%) | 1 (100%) |
| Non-European | 72 (23%) | 52 (23%) | 11 (22%) | 4 (27%) | 5 (28%) | 0 (0%) |
| Missing | 51 (17%) | 39 (17%) | 6 (12%) | 2 (13%) | 4 (22%) | 0 (0%) |
| Diagnosis type | ||||||
| Newly diagnosed | 251 (82%) | 185 (83%) | 36 (73%) | 13 (87%) | 16 (89%) | 1 (100%) |
| Refractory | 19 (6.2%) | 16 (7.1%) | 3 (6.1%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Relapsed | 37 (12%) | 23 (10%) | 10 (20%) | 2 (13%) | 2 (11%) | 0 (0%) |
1
data summarized as median (IQR) and n (%); AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; MPAL, mixed phenotypic acute leukemia; IQR, interquartile range.