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. 2023 Dec 4;17(6):064103. doi: 10.1063/5.0170606

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© 2023 Author(s).

All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Published open access through an agreement with Politecnico di Milano18981

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FIG. 5. — Permeability analysis within the liver sinusoid models generated in the devices after being exposed to static or dynamic culture conditions. (a) Images of the 40 kDa RFP-Dextran flowing within the lumen immediately after injection (t = 0) and after 30 min (t = 30). Scale bars are 140 μm. (b) Cross-diameter bell-curve distribution of the fluorescent intensity immediately after RFP-Dextran injection and after 30 min in PHH-only (left) and in PHH/HUVEC (right) conditions within (i) direct-contact device (DC) and (ii) ECM-mediated-contact device (ECM), either cultured in static (-S) or dynamic conditions (-D).