Table 2.
Baseline characteristics of patients before and after propensity score matching
| Characteristics | Before matching | p value | After matching | p value | ||||
|---|---|---|---|---|---|---|---|---|
| overall (n = 174) |
central arm (n = 64) |
peripheral arm (n = 110) |
overall (n = 96) |
central arm (n = 48) |
peripheral arm (n = 48) |
|||
| Age (mean±SD), years | 71.2±9.8 | 70.2±11.5 | 71.8±8.5 | 0.688 | 70.3±9.5 | 71.2±10.6 | 69.4±8.1 | 0.231 |
| Sex (male/female) | 120/54 | 48/16 | 72/38 | 0.189 | 69/27 | 35/13 | 34/14 | 0.820 |
| Etiology (viral/nonviral) | 129/45 | 43/21 | 86/24 | 0.110 | 73/23 | 34/14 | 39/9 | 0.232 |
| Child-Pugh score (mean±SD) | 5.85±1.13 | 5.77±1.07 | 5.90±1.17 | 0.515 | 5.94±1.20 | 5.83±1.10 | 6.04±1.30 | 0.529 |
| Child-Pugh (A/B) | 130/44 | 49/15 | 81/29 | 0.669 | 71/25 | 36/12 | 35/13 | 0.816 |
| ALBI score (mean±SD) | −2.37±0.52 | −2.38±0.49 | −2.36±0.54 | 0.870 | −2.30±0.53 | −2.35±0.48 | −2.25±0.57 | 0.505 |
| ALBI grade (1/2a/2b/3) | 64/37/65/8 | 23/15/24/2 | 41/22/41/6 | 0.868 | 32/20/37/7 | 16/12/18/2 | 16/8/19/5 | 0.549 |
| BCLC (0/A/B) | 9/92/73 | 1/30/33 | 8/62/40 | 0.065 | 4/54/38 | 1/26/21 | 3/28/17 | 0.474 |
| Largest tumor diameter (mean±SD), cm | 3.5±2.2 | 4.5±3.0 | 3.0±1.3 | <0.001* | 3.4±1.5 | 3.4±1.5 | 3.3±1.5 | 0.538 |
| Largest tumor diameter (n) (≤5 cm/>5 cm) | 151/23 | 49/15 | 102/8 | 0.002* | 85/11 | 44/4 | 41/7 | 0.336 |
| Tumor number/patient (median, range) | 2 (1–150) | 2 (1–82) | 2 (1–150) | 0.132 | 2 (1–100) | 2 (1–82) | 1(1–100) | 0.199 |
| Tumor number (n) (<4/≥4) | 123/51 | 40/24 | 83/27 | 0.070 | 70/26 | 31/17 | 39/9 | 0.066 |
| Up-to-7 criteria (n) (in/out) | 121/53 | 37/27 | 84/26 | 0.010* | 70/26 | 33/15 | 37/11 | 0.358 |
| AFP, ng/mL (median, range) | 13.8 (2–1,039,586) | 19.6 (2–1,039,586) | 12.7 (2–5,732.5) | 0.360 | 13.5(2–5,732.5) | 11.5(2–3,479.1) | 14.1(2–5,732.5) | 0.287 |
| AFP (n) (<400 ng/mL/≥400 ng/mL) | 147/27 | 51/13 | 96/14 | 0.183 | 83/13 | 42/6 | 41/7 | 0.766 |
| PIVKA-II, mAU/mL (median, range) | 153 (9–238,237) | 236 (10–238,237) | 120 (9–27,289) | 0.010* | 142(10–34,603) | 144(10–34,603) | 133(12–19,441) | 0.421 |
| PIVKA-II (n) (<300 mAU/mL/≥300 mAU/mL) | 108/66 | 35/29 | 73/37 | 0.126 | 62/34 | 32/16 | 30/18 | 0.670 |
ALBI, albumin-bilirubin; BCLC, Barcelona Clinic Liver Cancer; AFP, α-fetoprotein; PIVKA-II, protein induced by vitamin K absence or antagonists-II.
*p value <0.05.