Fig. 2.

Schematic diagram of neuronal LD formation and cholesterol synthesis and lipids transport between brain cell types. Also shown are genetic risk factors and other risk factors (stress or aging) that may affect neural lipid synthesis, metabolism, and transport in developing AD or NPDs. OPC, oligodendrocyte precursor cells; CE, cholesterol ester; FFA, free fatty acids; LDs, lipid droplets; TC, triacsin C; AD, Alzheimer’s disease; NPDs, non-AD neuropsychiatric disorders. The figure was partially created with www.biorender.com.