Table 2.
Subgroup analysis of the mean estimates of serum 25(OH)D, PTH, calcium and magnesium in morbidly obese patients or bariatric surgery candidates based on geographical zones
| Subgroup | Included studies | Sample size | Pooled mean estimate | 95% confidence interval | Heterogeneity I2, % |
|---|---|---|---|---|---|
| Serum 25(OH)D, ng/mL, total | 96 | 18,998 | 18.65 | 17.85, 19.45 | 99.4 |
| Europe | 50 | 18.94 | 17.86, 20.02 | 99.5 | |
| North America | 16 | 21.71 | 19.69, 23.74 | 97.2 | |
| South America | 6 | 21.12 | 16.07, 26.16 | 99.1 | |
| Australia | 5 | 17.77 | 14.90, 20.63 | 79.1 | |
| Middle East | 17 | 15.29 | 13.93, 16.65 | 98.3 | |
| Southeast Asia | 2 | 14.93 | 14.54–15.33 | 0.0 | |
| Serum PTH, pg/mL, total | 56 | 11,545 | 59.24 | 54.98, 63.51 | 99.7 |
| Europe | 31 | 62.88 | 56.17–69.58 | 99.8 | |
| North America | 10 | 56.3 | 50.18–62.43 | 96.2 | |
| South America | 2 | 67.3 | 63.08–71.52 | 0.0 | |
| Australia | 4 | 51.4 | 47.61–55.19 | 59.8 | |
| Middle East | 7 | 53.05 | 47.21–58.89 | 97.5 | |
| Southeast Asia | 2 | 45.92 | 33.11–55.73 | 93.8 | |
| Serum calcium, mg/dL, total | 53 | 13,355 | 9.26 | 9.19–9.32 | 99.7 |
| Europe | 28 | 9.28 | 9.16, 9.39 | 99.8 | |
| North America | 9 | 9.32 | 9.19, 9.44 | 98.1 | |
| South America | 3 | 9.00 | 8.53, 9.48 | 99.2 | |
| Australia | 4 | 9.36 | 9.25, 9.47 | 98.2 | |
| Middle East | 7 | 9.19 | 9.04, 9.35 | 99.8 | |
| Southeast Asia | 2 | 9.03 | 8.58, 9.48 | 99.5 | |
| Serum magnesium, mg/dL, total | 13 | 2,527 | 0.91 | 0.84, 0.98 | 100.0 |
| Europe | 9 | 0.81 | 0.79, 0.82 | 98.8 | |
| North America | 2 | 1.44 | 0.77, 2.11 | 99.7 | |
| South America | – | – | – | – | – |
| Australia | – | – | – | – | – |
| Middle East | 2 | 0.91 | 0.72, 1.09 | 99.9 | |
| Southeast Asia | – | – | – | – | – |