Table 2.
ccRCC overall survival analysis.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Gender | 541 | 0.614 | |||
| Female | 187 | Reference | |||
| Male | 354 | 0.924 (0.679–1.257) | 0.613 | ||
| Age | 541 | <0.001 | |||
| ≤60 | 269 | Reference | Reference | ||
| >60 | 272 | 1.791 (1.319–2.432) | <0.001 | 1.728 (1.046–2.854) | 0.033 |
| Serum calcium | 367 | 0.076 | |||
| Low | 204 | Reference | Reference | ||
| Normal and elevated | 163 | 1.356 (0.969–1.899) | 0.076 | 0.622 (0.380–1.018) | 0.059 |
| Histologic grade | 533 | <0.001 | |||
| G1 and G2 | 250 | Reference | Reference | ||
| G3 and G4 | 283 | 2.665 (1.898–3.743) | <0.001 | 0.985 (0.560–1.735) | 0.960 |
| Pathologic T stage | 541 | <0.001 | |||
| T1 and T2 | 350 | Reference | Reference | ||
| T3 and T4 | 191 | 3.210 (2.373–4.342) | <0.001 | 2.207 (1.304–3.737) | 0.003 |
| Pathologic N stage | 258 | 0.001 | |||
| N0 | 242 | Reference | Reference | ||
| N1 | 16 | 3.422 (1.817–6.446) | <0.001 | 0.829 (0.308–2.232) | 0.710 |
| Pathologic M stage | 508 | <0.001 | |||
| M0 | 429 | Reference | Reference | ||
| M1 | 79 | 4.401 (3.226–6.002) | <0.001 | 5.154 (2.926–9.080) | <0.001 |
| RBMS2 | 541 | <0.001 | |||
| Low | 270 | Reference | Reference | ||
| High | 271 | 0.545 (0.399–0.744) | <0.001 | 0.719 (0.436–1.184) | 0.195 |
Bold values indicate P<0.05.