Table 3.
ccRCC disease-free survival analysis.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Gender | 530 | 0.415 | |||
| Female | 181 | Reference | |||
| Male | 349 | 1.183 (0.786–1.781) | 0.420 | ||
| Age | 530 | 0.117 | |||
| ≤60 | 265 | Reference | |||
| >60 | 265 | 1.351 (0.926–1.971) | 0.118 | ||
| Serum calcium | 361 | 0.056 | |||
| Low | 200 | Reference | Reference | ||
| Normal and elevated | 161 | 1.507 (0.989–2.298) | 0.057 | 0.570 (0.312–1.041) | 0.067 |
| Histologic grade | 522 | <0.001 | |||
| G1 and G2 | 249 | Reference | Reference | ||
| G3 and G4 | 273 | 4.850 (2.925–8.043) | <0.001 | 0.936 (0.429–2.039) | 0.867 |
| Pathologic T stage | 530 | <0.001 | |||
| T1 and T2 | 347 | Reference | Reference | ||
| T3 and T4 | 183 | 5.606 (3.697–8.502) | <0.001 | 3.590 (1.752–7.358) | <0.001 |
| Pathologic N stage | 256 | 0.003 | |||
| N0 | 241 | Reference | Reference | ||
| N1 | 15 | 3.864 (1.831–8.157) | <0.001 | 0.764 (0.274–2.124) | 0.605 |
| Pathologic M stage | 497 | <0.001 | |||
| M0 | 422 | Reference | Reference | ||
| M1 | 75 | 9.219 (6.294–13.504) | <0.001 | 9.294 (4.797–18.004) | <0.001 |
| RBMS2 | 530 | <0.001 | |||
| Low | 265 | Reference | Reference | ||
| High | 265 | 0.352 (0.229–0.540) | <0.001 | 0.387 (0.203–0.737) | 0.004 |
Bold values indicate P<0.05.