Table 3.
Correlation between baseline magnetic resonance biomarkers and 12-month follow-up functional abilities in Duchenne muscular dystrophy
| Variable | T1 (ms) | Fat fraction (%) | ||||||
|---|---|---|---|---|---|---|---|---|
| Flexors | Extensors | Adductor | Abductors | Flexors | Extensors | Adductor | Abductors | |
| Age | −0.206a | −0.304b | −0.314b | −0.262b | 0.360b | 0.418b | 0.422b | 0.341b |
| Height | −0.167 | −0.219a | −0.218a | −0.190a | 0.297b | 0.275b | 0.317b | 0.229a |
| Weight | −0.181 | −0.350b | −0.307b | −0.313b | 0.437b | 0.446b | 0.397b | 0.417b |
| BMI | −0.178 | −0.367b | −0.287b | −0.306b | 0.396b | 0.433b | 0.317b | 0.401b |
| Wheelchair use | −0.163 | −0.137 | −0.151 | −0.158 | 0.163 | 0.157 | 0.163 | 0.160 |
| NSAA | 0.480c | 0.510c | 0.620c | 0.554c | −0.741c | −0.701c | −0.783c | −0.762c |
| 10m run/walk | −0.461c | −0.481c | −0.670c | −0.510c | 0.736c | 0.691c | 0.787c | 0.729c |
| Gowers | −0.455c | −0.463c | −0.625c | −0.422c | 0.650c | 0.623c | 0.745c | 0.650c |
| 4-stair climb | −0.458c | −0.443c | −0.622c | −0.470c | 0.686c | 0.602c | 0.737c | 0.702c |
| 4-stair descend | −0.444c | −0.413c | −0.557c | −0.483c | 0.659c | 0.596c | 0.668c | 0.655c |
Significant differences are marked as aP<0.05, bP<0.01, cP<0.0001
BMI body mass index, NSAA North Star Ambulatory Assessment