Table 4.
Univariate and multivariate logistic regression for predicting future motor function decline in Duchenne muscular dystrophy
| Variable | Univariate analysis | Multivariate analysis (model 1) | Multivariate analysis (model 2) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-valuea | OR | 95% CI | P-valuea | |
| T1 (ms) | |||||||||
| Flexors | 0.997 | 0.994~0.999 | 0.006 | 1.000 | 0.995~1.005 | 0.914 | 1.001 | 0.996~1.005 | 0.832 |
| Extensors | 0.995 | 0.993~0.998 | 0.000 | 0.999 | 0.995~1.004 | 0.785 | 0.999 | 0.995~1.004 | 0.700 |
| Adductors | 0.997 | 0.995~0.998 | 0.001 | 1.002 | 0.998~1.006 | 0.444 | 1.002 | 0.998~1.007 | 0.292 |
| Abductors | 0.997 | 0.995~0.998 | 0.000 | 1.001 | 0.997~1.004 | 0.650 | 1.001 | 0.997~1.004 | 0.655 |
| Fat fraction (%) | |||||||||
| Flexors | 1.123 | 1.064~1.184 | 0.000 | 0.980 | 0.883~1.088 | 0.706 | / | / | / |
| Extensors | 1.098 | 1.055~1.143 | 0.000 | 1.026 | 0.940~1.121 | 0.564 | 1.003 | 0.920~1.094 | 0.941 |
| Adductors | 1.090 | 1.050~1.131 | 0.000 | / | / | / | 1.036 | 0.957~1.122 | 0.377 |
| Abductors | 1.099 | 1.055~1.145 | 0.000 | 1.104 | 1.026~1.187 | 0.008 | 1.085 | 1.013~1.161 | 0.019 |
| Age(y) | 1.338 | 1.033~1.733 | 0.028 | 1.071 | 0.764~1.499 | 0.691 | 1.038 | 0.735~1.467 | 0.831 |
| BMI (kg/m2) | 1.117 | 0.959~1.301 | 0.156 | / | / | / | / | / | / |
| Corticosteroid use | 6.250 | 1.809~21.589 | 0.004 | 3.915 | 0.621~24.687 | 0.146 | 3.857 | 0.663~22.435 | 0.133 |
BMI body mass index, CI confidence internal, DMD Duchenne muscular dystrophy, OR odds ratio
aP-value <0.05 is significant (bold)