Table 2.

List of NLRP3 Inflammasome Inhibitors

Component	Target	Effect	Ref
Parthenolide	NLRP3	Blocks ATPase activity	[225]
Bay 11–7082	NLRP3	Blocks ATPase activity	[225]
CY-09	NLRP3	Blocks ATPase activity	[226]
Dapansutrile	NLRP3	Blocks ATPase activity	[227]
INF148/INF120/INF156/INF172	NLRP3	Blocks ATPase activity	[228]
MNS	NLRP3	Blocks ATPase activity	[229]
Oridonin	NLRP3	Prevents oligomerization	[230]
Tranilast	NLRP3	Prevents oligomerization	[231]
11Cha1	ASC	Prevents oligomerization	[232]
MCC950	ASC	Blocks ATPase activity	[233]
Ac-YVAD-CHO	CASP1	Blocks protease activity	[234]
Belcanasan	CASP1	Blocks protease activity	[223]
Parthenolide	CASP1	Blocks protease activity	[225]
Pralnacasan	CASP1	Blocks protease activity	[235]
Thalidomide	CASP1	Blocks protease activity	[236]