Table 3.

Twenty-four hour Holter monitoring

	Baseline	6 months	1 year	2 years	3 years	Annual change (95% CI)	p value
	(N = 20)	(N = 19)	(N = 19)	(N = 19)	(N = 19)
Heart rate (beats/minute), median [25th–75th percentiles]	71 [60–75]	66 [63–70]	71 [62–76]	68 [60–73]	68 [65–73]	− 0.3 (− 1.7, 1.1) beats/minute	0.68
Supraventricular ectopic beats (n), median [25th–75th percentiles]	187 [87–898]	218 [58–1173]	79 [26–564]	283 [79–608]	282 [99–1359]	15.2% (− 9.0%, 45.8%)	0.24
Ventricular ectopic beats (n), median [25th–75th percentiles]	35 [4–149]	22 [4–85]	42 [6–105]	29 [11–390]	89 [41–269]	54.8% (19.7%, 100.3%)	< 0.001

CI confidence interval, SD standard deviation