Table 4.

Average total volume of distribution (V_T), and 2TCM fit weighted symmetrical mean absolute percentage error (wsMAPE) for mice anesthetized with isoflurane or ketamine-xylazine

	Isoflurane				Ketamine-xylazine
	VT (ml/cm3)		wsMAPE (%)		VT (ml/cm3)		wsMAPE (%)
	IDIF	NMF-IDIF	IDIF	NMF-IDIF	IDIF	NMF-IDIF	IDIF	NMF-IDIF
CTX	29.8 $\pm$ 1.86	30.9 $\pm$ 1.94	1.16 $\pm$ 0.33	0.918 $\pm$ 0.27	10.6 $\pm$ 1.34	14.0 $\pm$ 1.81	2.28 $\pm$ 1.21	1.12 $\pm$ 0.44
CP	24.7 $\pm$ 1.90	25.7 $\pm$ 1.83	1.56 $\pm$ 0.34	1.23 $\pm$ 0.28	9.54 $\pm$ 1.25	12.5 $\pm$ 1.72	2.53 $\pm$ 1.28	1.28 $\pm$ 0.41
TH	34.9 $\pm$ 2.17	36.3 $\pm$ 2.35	1.99 $\pm$ 0.63	1.58 $\pm$ 0.61	12.9 $\pm$ 1.84	17.6 $\pm$ 3.37	3.04 $\pm$ 1.57	1.78 $\pm$ 0.53
HC	31.2 $\pm$ 1.54	32.5 $\pm$ 1.83	1.47 $\pm$ 0.34	1.17 $\pm$ 0.39	12.0 $\pm$ 1.62	15.7 $\pm$ 2.15	2.60 $\pm$ 1.28	1.35 $\pm$ 0.39
CB	22.1 $\pm$ 2.15	22.9 $\pm$ 1.83	1.59 $\pm$ 0.35	1.32 $\pm$ 0.29	8.23 $\pm$ 0.99	10.9 $\pm$ 1.39	2.63 $\pm$ 0.91	1.48 $\pm$ 0.39

CTX cortex, CP caudate putamen, TH thalamus, HC hippocampus, CB cerebellum