Table 3.
Adjusted hazard ratios of 5-year surgical complications after midurethral sling surgery, stratified by subgroups of age and diabetes mellitus.
| Available N | No. of events | HR (95% CI) | |
|---|---|---|---|
| Age ≤ 65 years | |||
| Diabetes mellitus | |||
| No | 1429 | 50 | Ref |
| Yes | 94 | 5 | 1.793 (0.669, 4.807) |
| Surgical duration (h) | 1523 | 55 | 1.111 (0.912, 1.355) |
| Menopausal syndrome diagnosis | |||
| No | 1389 | 45 | Ref |
| Yes | 134 | 10 | 2.222 (0.982, 5.029) |
| Hormone replacement therapy | |||
| No | 1360 | 42 | Ref |
| Yes | 163 | 13 | 1.384 (0.596, 3.215) |
| Average flow rate (ml/s) | 1423 | 55 | 0.929 (0.853, 1.012) |
| TVT-O sling type | |||
| TOT | 475 | 12 | Ref |
| TVT-O | 885 | 32 | 1.235 (0.598, 2.547) |
| Age > 65 years | |||
| Diabetes mellitus | |||
| No | 354 | 30 | Ref |
| Yes | 84 | 8 | 1.185 (0.476, 2.952) |
| Surgical duration (h) | 438 | 38 | 0.966 (0.697, 1.338) |
| Menopausal syndrome diagnosis | |||
| No | 378 | 33 | Ref |
| Yes | 60 | 5 | 0.618 (0.146, 2.618) |
| Hormone replacement therapy | |||
| No | 316 | 21 | Ref |
| Yes | 122 | 17 | 2.131 (0.880, 5.163) |
| Average flow rate (ml/s) | 423 | 35 | 1.036 (0.893, 1.201) |
| TVT-O sling type | |||
| TOT | 145 | 7 | Ref |
| TVT-O | 253 | 23 | 1.392 (0.516, 3.754) |
| Diabetes mellitus | |||
| Age (year) | 178 | 13 | 1.013 (0.959, 1.069) |
| Surgical duration (h) | 178 | 13 | 1.630 (0.971, 2.735) |
| Menopausal syndrome diagnosis | |||
| No | 162 | 12 | Ref |
| Yes | 16 | 1 | 0.000 (0.000, 0.000) |
| Hormone replacement therapy | |||
| No | 143 | 10 | Ref |
| Yes | 35 | 3 | 0.340 (0.036, 3.207) |
| Average flow rate (ml/s) | 170 | 12 | 1.049 (0.923, 1.193) |
| TVT-O sling type | |||
| TOT | 83 | 4 | Ref |
| TVT-O | 87 | 8 | 1.249 (0.400, 3.895) |
| Non-diabetes mellitus | |||
| Age (year) | 1783 | 80 | 1.015 (0.989, 1.041) |
| Surgical duration (h) | 1783 | 80 | 1.023 (0.847, 1.235) |
| Menopausal syndrome diagnosis | |||
| No | 1605 | 66 | Ref |
| Yes | 178 | 14 | 1.504 (0.743, 3.046) |
| Hormone replacement therapy | |||
| No | 1533 | 53 | Ref |
| Yes | 250 | 27 | 2.239 (1.235, 4.057)*,a |
| Average flow rate (ml/s) | 1676 | 78 | 0.940 (0.860, 1.028) |
| TVT-O sling type | |||
| TOT | 537 | 15 | Ref |
| TVT-O | 1051 | 47 | 1.191 (0.611, 2.321) |
CI, confidence interval; HR, hazard ratio; TOT, transobturator tape; TVT-O, tension-free vaginal tape-obturator.
*Statistically significant.
aP for interaction with hormone replacement therapy was 0.0807.