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. 2023 Dec 5;13:25. doi: 10.1038/s41387-023-00255-1

Table 2.

A synergistic impact of BMI and gamma gap on heart failure with different adjustment models.

Heart failure Hazard ratio (95% confidence interval), P value
High BMI, low gamma gap (n = 286) Low BMI, low gamma gap (n = 387) High BMI, high gamma gap (n = 128) Low BMI, high gamma gap (n = 186)
Model 1 Reference 1.79 (1.24–2.59), P = 0.002 2.03 (1.26–3.26), P = 0.004 3.70 (2.44–5.59), P <0.001
Model 2 Reference 1.76 (1.20–2.56), P = 0.004 1.82 (1.11–2.99), P = 0.017 3.76 (2.45–5.77), P <0.001
Model 3 Reference 1.62 (1.08–2.42), P = 0.019 1.58 (0.94–2.65), P = 0.082 2.82 (1.79–4.48), P <0.001

Model 1: unadjusted; model 2: adjusted for age and sex; model 3: adjusted for age, gender, heart rate, diastolic blood pressure, hemoglobin, albumin, high density lipoprotein cholesterol, creatinine, fasting plasma glucose, C-reactive protein and N-terminal pro-brain natriuretic peptide.

BMI body mass index.