Fig. 8.

Serum LPS, fecal albumin, and serum PAA levels in cohoused littermate WT and Shp^−/− mice. A: Concentrations of serum LPS and fecal albumin were quantified in cohoused WT and Shp^−/− mice generated by heterozygous mating using commercial ELISA kits. The average values were plotted with SEM (n = 6). B: PAA levels were measured in the blood collected from portal veins of 4-month-old cohoused mice on 2 month diet regimen after 5 h fasting using a GC-MS. Average mean values were presented with SEM (n = 5–6). Two-way ANOVA was used to evaluate statistical significances. Student's t-test was also performed to evaluate statistical significance. #comparison with CD, ∗comparison with WT counterparts. Two symbols represent P < 0.01, and one symbol represents P < 0.05.