Fig. 6.

Disulfidptosis-related SCNAs among cancer types. (A) Disulfidptosis-related SCNAs across multiple cancers. The upper bar denotes the number of cancer types with amplifications (magenta) or deletions (green); the right bar denotes the number of amplifications (magenta) or deletions (green) in each cancer. Upper triangles denote the disulfidptosis score-high; Inverted triangles denotes the disulfidptosis score-low. (B) Chromosome plot displays locations of disulfidptosis-related SCNAs with significant alterations or harbored genes in the disulfidptosis score-high group vs. the disulfidptosis score-low group. Magenta indicates amplification in the disulfidptosis score-high group; green indicates amplification in the disulfidptosis score-low group. Pink indicates deletion in the disulfidptosis score-high group; light blue indicates deletion in the disulfidptosis score-low group. The purple label shows clinical actionable genes (CAGs). (C) FDA-approved drugs targeting CAGs in disulfidptosis-related SCNAs. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)