Table 2.
Comparison of mean ± SD of whole blood GLUT 1 mRNA fold changes, serum levels of IL-6, fetuin-A, PTX3, and PEDF by the PASI score categories in psoriatic patients (G2).
| PASI score categories | p value | ||||
|---|---|---|---|---|---|
| Mild n = 5 |
Moderate n = 20 |
Severe n = 8 |
Very severe n = 11 |
||
| GLUT 1 mRNA fold changes | 4.7 ± 0.9 | 6.6 ± 2.3 | 9.5 ± 2.2 | 11.7 ± 3.4 | < 0.001 |
| PEDF (ng/ml) | 23.7 ± 7.1 | 16.1 ± 3.8 | 12.6 ± 2.6 | 9.9 ± 2.9 | < 0.001 |
| Serum IL-6 (pg/ml) | 18.9 ± 5.1 | 24.9 ± 8.9 | 29.2 ± 1.6 | 34.7 ± 4.9 | < 0.001 |
| Serum fetuin-A (µg/ml) | 80.8 ± 15.2 | 86.6 ± 16.8 | 91.4 ± 5.1 | 107.7 ± 4.9 | 0.001 |
| Serum PTX3 (ng/ml) | 2.6 ± 0.5 | 3.5 ± 0.7 | 3.7 ± 0.4 | 4.3 ± 0.4 | < 0.001 |
One-way analysis of variance (ANOVA) test was used to compare the mean between groups. SD standard deviation, PASI psoriasis area and severity index, GLUT 1 glucose transporter type 1 gene, mRNA messenger ribonucleic acid, PEDF serum pigment epithelium-derived factor, IL-6 interleukin-6, PTX3 pentraxin-3.