Table 2.
Sensitivity, specificity, accuracy, and Cohen’s kappa () of classifying target mismatch criteria with model-independent deconvolution versus model-dependent deconvolution and CT Perfusion 4D (CTP4D) software.
| Criteria | Sensitivity (%) | Specificity (%) | Accuracy (%) | (95% CI) |
|---|---|---|---|---|
| Model-dependent | ||||
| Target mismatch profile | 47/50 (94) | 13/13 (100) | 60/63 (95) |
0.87 (0.72–1.00) |
| Core < 70 ml | 53/55 (96) | 8/8 (100) | 61/63 (97) |
0.87 (0.70–1.00) |
| Penumbra ≥ 15 ml | 61/61 (100) | 2/2 (100) | 63/63 (100) |
1.00 (1.00–1.00) |
| Mismatch ratio ≥ 1.8 | 52/54 (96) | 5/9 (56) | 57/63 (90) |
0.57 (0.27–0.88) |
| CT Perfusion 4D (CTP4D) | ||||
| Target mismatch profile | 48/50 (96) | 12/13 (92) | 60/63 (95) |
0.86 (0.70–1.00) |
| Core < 70 ml | 53/55 (96) | 6/8 (75) | 59/63 (94) |
0.71 (0.45–0.98) |
| Penumbra ≥ 15 ml | 61/61 (100) | 2/2 (100) | 63/63 (100) |
1.00 (1.00–1.00) |
| Mismatch ratio ≥ 1.8 | 53/54 (98) | 5/9 (56) | 58/63 (92) |
0.62 (0.33–0.92) |