Table 3.

Patient motivation to use the MEMS versus their therapy adherence

	All four groups			Application driven
	One monitoring (n = 131)	Both monitorings (n = 483)	p value	Two separate monitorings* (n = 47)	Whole study period* (n = 37)	p value
Therapy adherence, mean ± SD	92.0 ± 13.9	94.3 ± 9.8	0.060	93.1 ± 8.0%	96.3 ± 4.8%	0.067
Therapy adherence, mean ± SD		94.5 ± 9.1		92.5 ± 7.1%	96.2 ± 5.3%	0.048
p value		0.538		0.675	0.717

^*Two separate monitorings: patients who used the medication bottle during the two monitoring periods separately vs. Whole study period: patients who used the medication bottle during the full 15 months of study period; P values were calculated with the Mann–Whitney U test with in bold p < 0.05