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Clinical characteristics over time by BW reduction categories. BW (A), waist circumference (B), HbA1c (C), systolic blood pressure (D), triglycerides (E), and ALT (F). Data are least squares mean (SE) actual values over time from baseline to week 40. Least squares mean values were calculated from mixed-model repeated-measures model: value = treatment + time + treatment ∗ time.
