Table 1.
Literature review of the immunohistochemistry of minute pulmonary meningothelial-like nodules
| Ref. | Number of nodules/lesions evaluated |
Immunophenotype
|
|||||||||||
|
EMA
|
VIM
|
PR
|
CD56
|
SSTR2a
|
CK
|
Syn
|
Actin
|
S100
|
HMB-45
|
NSE
|
CgA
|
||
| Bernabeu et al[13], 2013 | 1 | 1/0a | 1/0 | 1/0 | 1/0 | – | 0/1 | 0/1 | 0/1 | – | 0/1 | – | 0/1 |
| Lee et al[18], 2013 | 1 | 1/0 | 1/0 | 1/0 | 1/0 | – | 0/1 | – | – | – | – | – | – |
| Tao et al[4], 2019 | 39 | 29/10 | – | 11/28 | – | 39/0 | 0/39 | 0/39 | – | 0/39 | – | – | 0/39 |
| Niho et al[6], 1999 | 29 | 22/0b | 29/0 | 9/9 | – | – | 0/29 | 2/27 | – | 10/11 | 0/28 | 25/4 | 1/28 |
| Pelosi et al[21], 2002 | 9 | 9/0 | 9/0 | 9/0 | – | – | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 | – | – |
| Peng et al[8], 2019 | 8 | 7/0 | 8/0 | 6/0 | – | – | 0/2 | – | – | – | – | – | – |
| Agozzino et al[19], 2006 | 1 | 1/0 | 1/0 | 0/1 | – | – | 0/1 | 0/1 | 0/1 | 0/1 | – | 0/1 | 0/1 |
| Kfour et al[20], 2012 | 2 | 2/0 | 2/0 | 2/0 | – | – | – | – | – | – | – | – | – |
| Torikata et al[5], 1990 | 24 | 0/18 | 24/0 | – | – | – | 0/17 | – | 0/21 | 0/16 | – | 0/17 | – |
| Gaffey et al[10], 1988 | 14 | 12/2 | 10/2 | – | – | – | 0/14 | – | 0/7 | 0/14 | – | 0/14 | – |
| Harada et al[7], 2019 | 1 | 1/0 | 1/0 | 1/0 | 1/0 | NR | NR | NR | NR | NR | NR | NR | NR |
| Total | 129 | 85/30 | 86/2 | 40/38 | 3/0 | 39/0 | 0/110 | 2/74 | 0/36 | 10/87 | 0/35 | 25/36 | 1/68 |
a
Number of lesions with positive immunocytochemical staining/negative immunocytochemical staining.
b
Not all nodules/lesions are evaluated for specific immunophenotypes.
EMA: Epithelial membrane antigen; VIM: Vimentin; PR: Progesterone receptor; SSTR2a: Somatostatin receptor 2a; CK: Cytokeratin; Syn: Synaptophysin; NSE: Neuron-specific enolase; CgA: Chromogranin A; NR: Not reported; –: Not evaluated.