Table 2.
Associations of variables with leucine-rich α-2 glycoprotein to predict remission
|
Variable
|
Cut-off value (μg/mL)
|
AUC
|
95%CI
|
SENS (%)
|
SPEC (%)
|
PPV (%)
|
PLR
|
| PMS 0 | 12.9 | 0.951 | 0.873-1.000 | 89 | 91 | 94 | 10.6 |
| MES 0 | 13.4 | 0.871 | 0.744-0.998 | 100 | 64 | 68 | 2.8 |
| UCEIS 0,1 | 13.4 | 0.904 | 0.792-1.000 | 100 | 69 | 73 | 3.2 |
| Matts grade 1 | 9.7 | 0.889 | 0.755-1.000 | 100 | 81 | 37 | 5.4 |
| Riley’s score 0,1 | 13.4 | 0.739 | 0.550-0.929 | 100 | 46 | 32 | 1.8 |
| GHS 0,1 | 13.4 | 0.679 | 0.477-0.880 | 92 | 59 | 63 | 2.2 |
LRG: Leucine-rich α-2 glycoprotein; AUC: Area under the curve; CI: Confidence interval; SENS: Sensitivity; SPEC: Specificity; PPV: Positive predictive value; PLR: Positive likelihood ratio; MS: Mayo Score; MES: Mayo Endoscopic Subscore; UCEIS: Ulcerative Colitis Endoscopic Index of Severity; GHS: Geboes Histopathology Score.