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| Compound | HeLa IC50a,b (μM) | cLogPc |
|---|---|---|
| 8 | 0.044 ± 0.011 | 3.3 |
| 26 | >4.0 | 2.9 |
| 27 | >4.0 | 2.9 |
| 31 | >4.0 | 2.9 |
| 34 | 0.78 ± 0.20 | 3.5 |
| 36 | 1.1 ± 0.4 | 3.4 |
Data represent the mean of three independent determinations from triplicate samples.
IC50 values were determined using the CCK-8 assay in HeLa cells.
cLogP values were calculated using online ALOGPS 2.1 program.
