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. 2023 Oct 20;5(6):e230078. doi: 10.1148/rycan.230078

Figure 3:

Images from presurgical functional MRI (fMRI) for language mapping. (A) Sagittal fMRI scan in a 45-year-old woman with a left frontal low-grade glioma (arrow) shows close proximity of the lesion with the ventral premotor cortex (red) from a sentence completion task. Activation from a reading comprehension task is shown in magenta, with activation in the inferior frontal gyrus corresponding to the traditional Broca area. (B) In a second patient, a 73-year-old woman with a left frontal high-grade glioma, there is no activation present in the left hemisphere during a sentence completion task. (C) In the same patient, there is right hemisphere–dominant language function (blue) on the sentence completion task showing the ability of task-based fMRI to correctly help lateralize this atypical language organization, which was confirmed intraoperatively.

Images from presurgical functional MRI (fMRI) for language mapping. (A) Sagittal fMRI scan in a 45-year-old woman with a left frontal low-grade glioma (arrow) shows close proximity of the lesion with the ventral premotor cortex (red) from a sentence completion task. Activation from a reading comprehension task is shown in magenta, with activation in the inferior frontal gyrus corresponding to the traditional Broca area. (B) In a second patient, a 73-year-old woman with a left frontal high-grade glioma, there is no activation present in the left hemisphere during a sentence completion task. (C) In the same patient, there is right hemisphere–dominant language function (blue) on the sentence completion task showing the ability of task-based fMRI to correctly help lateralize this atypical language organization, which was confirmed intraoperatively.