Table III.

Samples of limitations of oral food challenges (OFCs)

Resources to treat allergic reactions of any severity and access to intensive care unit

Highly skilled and trained clinical team

Ideal conditions of OFC impair translation to real-life allergic reactions in community

Potential on-the-day desensitization with sequential dosing during OFC

Anxiety related to fear of experiencing allergic reactions

Need for standardized but food-specific dosing schedule

No absolute accuracy with OFC although it is the reference standard test