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. 2023 Nov 29;98:104880. doi: 10.1016/j.ebiom.2023.104880

Fig. 5.

Fig. 5

NIR-II fluorescence-guided surgery for HCC. (a) Color imaging of the mice. (b) BLI-CT 3D reconstruction of the tumor. (Tumor area: Gray dashed wireframe) (c) Fluorescence-guided surgery process. Step 1: white light examination for HCC lesions. Step 2: first resection under white light. Step 3: NIR-II fluorescence-guided examination for residual lesions. Step 4: Removal of residual lesions. (d) Quantitative analysis of intraoperative fluorescence intensity in livers (blue) and tumors (red) (n = 6) (∗∗∗∗p < 0.0001, Student's t-test). (e) Pathological results of all residual lesions (Scale bars: 500 μm, 50 μm, respectively). Imaging filter:1000 nmLP. Exposure time:300 ms. Excitation wavelength:808 nm. Laser power density: 21.10 mW/cm2. Imaging field of view: 10 cm.The type of camera sensor: InGaAs.