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. 2023 Dec 6;13(50):35629–35638. doi: 10.1039/d3ra06930c

Observed responses and predicted values of CNF yield.

Run Variables levels Response value (CNF yield) (%)
A B C D Experimental Predicted
1 0 (3) 0 (110) 0 (80) 0 (30) 85.0 84.4
2 1 (4) 0 (110) −1 (60) 0 (30) 72.0 71.9
3 0 (3) 0 (110) 0 (80) 0 (30) 83.3 84.4
4 −1 (2) 0 (110) −1 (60) 0 (30) 68.0 70.4
5 0 (3) −1 (100) 0 (80) 1 (40) 49.3 51.4
6 0 (3) 0 (110) 1 (100) −1 (20) 71.4 70.7
7 −1 (2) −1 (100) 0 (80) 0 (30) 47.6 47.5
8 −1 (2) 1 (120) 0 (80) 0 (30) 64.6 65.6
9 −1 (2) 0 (110) 1 (100) 0 (30) 66.3 69.2
10 1 (4) 0 (110) 0 (80) −1 (20) 71.4 70.8
11 0 (3) −1 (100) 1 (100) 0 (30) 57.8 54.8
12 0 (3) 0 (110) 1 (100) 1 (40) 74.8 76.4
13 1 (4) 1 (120) 0 (80) 0 (30) 69.7 71.1
14 0 (3) 1 (120) −1 (60) 0 (30) 68.0 66.8
15 0 (3) 0 (110) −1 (60) 1 (40) 62.9 63.4
16 0 (3) −1 (100) −1 (60) 0 (30) 52.7 51.2
17 0 (3) 0 (110) −1 (60) −1 (20) 76.5 76.3
18 0 (3) 1 (120) 0 (80) 1 (40) 61.2 61.9
19 0 (3) 1 (120) 0 (80) −1 (20) 71.4 72.1
20 0 (3) 1 (120) −1 (60) 0 (30) 74.8 72.1
21 0 (3) −1 (100) 0 (80) −1 (20) 47.6 49.7
22 1 (4) 0 (110) −1 (60) 0 (30) 81.6 81.8
23 1 (4) 0 (110) 0 (80) 1 (40) 79.9 78.4
24 1 (4) −1 (100) 0 (80) 0 (30) 56.1 56.3
25 −1 (2) 0 (110) 0 (80) 1 (40) 62.9 59.3
26 0 (3) 0 (110) 0 (80) 0 (30) 85.0 84.4
27 −1 (2) 0 (110) 0 (80) −1 (20) 78.2 75.5