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. Author manuscript; available in PMC: 2024 Nov 13.
Published in final edited form as: J Chem Inf Model. 2023 Oct 17;63(21):6681–6695. doi: 10.1021/acs.jcim.3c00780

Table 2.

Synergistic assay of both compounds against clinical strains of Salmonella typhi

SYNERGISTIC ASSAY BACTERIAL ISOLATES (Clinical) Salmonella typhi strains
S-1 S-2 S-3 S-4 S-5 S-6
Zone of inhibition (mm)
Top1+ Cephalosporin Chembridge-ID-5747390 18.6 20.3 18.3 20.3 18.3 19.3
Top2 Cephalosporin Chembridge-ID-32025297` 19.6 18.3 19.3 19.3 18.3 20.3
Positive Control Cephalosporin 8.6 9.4 10.6 10.6 10.3 9.4
Negative control DMSO 0 0 0 0 0 0