Table 3.
The biochemical and lymphocyte subsets examination of COVID-19 patients infected by Omicron variant with and without convulsion
| Parameters | Convulsion group (n = 102) | Non-convulsion group (n = 172) | Control group (n = 50) | P |
|---|---|---|---|---|
| Albumin(g/L) | 44.2 ± 2.2a | 42.6 ± 4.1b | 44.9 ± 2.7a | < 0.01 |
| Globulin(g/L) | 23.1(21.0–25.2)a | 23.2(19.5–27.2)a | 21.2(19.0–23.6)b | 0.027 |
| ALT(U/L) | 20.5(15.8–25.4)a | 22.9(14.6–42.1)a | 15.5(13.1–18.3)b | < 0.01 |
| AST(U/L) | 51.3(42.5–63.8)a | 51.8(36.7–72.5)a | 34.6(28.7–38.8)b | < 0.01 |
| ALP(U/L) | 224.9 ± 60.9a | 205.2 ± 78.9b | 258.9 ± 79.5c | < 0.01 |
| LDH(U/L) | 345.0(304.0–419.0)a | 372.4(308.5–449.8)a | 261(242–291)b | < 0.01 |
| C3(g/L) | 1.0(0.9–1.2) | 1.1(0.8–1.3) | 1.0(0.9–1.1) | 0.952 |
| C4(g/L) | 0.3(0.3–0.4)a | 0.3(0.2–0.4)a | 0.2(0.2–0.3)b | < 0.01 |
| IgA(g/L) | 0.4(0.2–0.8) | 0.3(0.1–1.2) | 0.6(0.2–1.0) | 0.226 |
| IgG(g/L) | 6.7(5.6–8.3) | 6.5(4.1–8.9) | 7.0(5.9–9.4) | 0.080 |
| IgM(g/L) | 1.0(0.7–1.3) | 0.8(0.5–1.3) | 0.9(0.6–1.4) | 0.050 |
| Ca2 + (< 1.12mmol/L) | 77(75.5) | 113(65.7) | [1.12–1.27] | 0.089 |
| Lactic acid (> 1.7mmol/L) | 55(53.9) | 133(77.3) | [0.5–1.7] | < 0.01 |
| D- Dimer (> 550ug/L) | 46(45.1) | 87(50.6) | [0–550] | 0.380 |
| lymphocyte subsets Log(/ul) | 3.2 ± 0.3a | 3.4 ± 0.3b | 3.6 ± 0.2c | < 0.01 |
| CD3+ count Log(/ul) | 3.0 ± 0.4a | 3.2 ± 0.4b | 3.4 ± 0.2c | < 0.01 |
| CD3+CD4+ count Log(/ul) | 2.7 ± 0.4a | 3.0 ± 0.4b | 3.2 ± 0.2c | < 0.01 |
| CD3+CD8+ count Log(/ul) | 2.5 ± 0.4a | 2.7 ± 0.4b | 3.0 ± 0.2c | < 0.01 |
| CD3−CD19+count Log(/ul) | 2.6 ± 0.4a | 2.7 ± 0.4a | 3.0 ± 0.2b | < 0.01 |
| NK count Log(/ul) | 2.2 ± 0.4a | 2.4 ± 0.4b | 2.5 ± 0.3b | < 0.01 |
The data presented as median (interquartile range), mean ± standard deviation, [reference value] and n (%). The univariate analyses were performed using Kruskal–Wallis for skewed distribution variables, ANOVA for normal distribution variables and the chi-square test for categorical variables
Abbreviation: ALT Alanine transaminase, AST Aspartate transaminase, ALP Alkaline phosphatase, LDH Lactate dehydrogenase
P < 0.05 between a, b and c