Table 5.
Association results between genetic variants in GAB1 gene, and percentage of EOS and IgE levels
| SNVs | Genotypes | EOS (%) | pa | IgE(IU/ml) | pb |
|---|---|---|---|---|---|
| rs1396527 | |||||
| G/G | 3.00(1.30–5.60) | 0.007 | 2.08 ± 0.60 | 0.848 | |
| G/T | 5.50(2.50–7.70) | 2.14 ± 0.51 | |||
| T/T | 3.70(2.20–6.70) | 2.18 ± 0.46 | |||
| rs17017425 | |||||
| T/T | 3.10(1.60–6.40) | 0.102 | 2.04 ± 0.50 | 0.390 | |
| C/T | 4.80(2.20–7.60) | 2.20 ± 0.58 | |||
| C/C | 6.80(3.90–8.30) | 2.12 ± 0.59 | |||
| rs1866756 | |||||
| G/G | 3.30(1.60–6.20) | 0.136 | 2.09 ± 0.58 | 0. 846 | |
| G/A | 4.80(2.60–7.18) | 2.14 ± 0.50 | |||
| A/A | 2.40(0.63–11.53) | 2.22 ± 0.58 | |||
| rs3805236 | |||||
| A/A | 3.50(1.60–6.15) | 0.309 | 2.09 ± 0.58 | 0.877 | |
| A/G | 4.45(2.40–7.18) | 2.15 ± 0.52 | |||
| G/G | 4.80(2.50–14.50) | 2.10 ± 0.41 | |||
| rs3805246 | |||||
| G/G | 3.50(1.60–6.48) | 0.240 | 2.10 ± 0.58 | 0. 064 | |
| G/A | 4.80(2.50–6.80) | 2.13 ± 0.50 | |||
| A/A | 2.40(0.63–11.53) | 2.22 ± 0.58 | |||
| rs3805254 | |||||
| A/A | 3.50(1.60–6.48) | 0.240 | 2.10 ± 0.58 | 0. 064 | |
| A/G | 4.80(2.50–6.80) | 2.13 ± 0.50 | |||
| G/G | 2.40(0.63–11.53) | 2.22 ± 0.58 |
The values p < 0.05 were in bold
Abbreviations: a Kruskal-Wallis H test for EOS distribution between genotypes in the asthma group; b ANOVA for lg (lgE) distribution between genotypes in the asthma group