Table 7.
Association between GAB1 gene SNVs and ICS response
| SNVs | Genotypes | ICS responders | ICS nonresponders | p | pa | pb |
|---|---|---|---|---|---|---|
| rs1396527 | ||||||
| G/G | 22(52.4) | 8(27.6) | 0.036 | 0.038 | 0.642 | |
| G/T | 16(38.1) | 20(69.0) | ||||
| T/T | 4(9.5) | 1(3.4) | ||||
| rs17017425 | ||||||
| T/T | 25(59.5) | 16(55.2) | 0.760 | 0.715 | > 0.999 | |
| T/C | 13(31.0) | 11(37.9) | ||||
| C/C | 4(9.5) | 2(6.9) | ||||
| rs1866756 | ||||||
| G/G | 23(54.8) | 14(48.3) | 0.283 | 0.591 | 0.265 | |
| G/A | 16(38.1) | 15(51.7) | ||||
| A/A | 3(7.1) | 0(0.0) | ||||
| rs3805236 | ||||||
| A/A | 22(52.4) | 14(48.3) | 0.542 | 0.734 | 0.510 | |
| A/G | 18(42.9) | 15(51.7) | ||||
| G/G | 2(4.8) | 0(0.0) | ||||
| rs3805246 | ||||||
| G/G | 23(54.8) | 14(48.3) | 0.230 | 0.591 | 0.265 | |
| G/A | 16(38.1) | 15(51.7) | ||||
| A/A | 3(7.1) | 0(0.0) | ||||
| rs3805254 | ||||||
| A/A | 23(54.8) | 14(48.3) | 0.230 | 0.591 | 0.265 | |
| A/G | 16(38.1) | 15(51.7) | ||||
| G/G | 3(7.1) | 0(0.0) |
The values p < 0.05 were in bold
a dominant model; b recessive model