Table 3.
Comparison of baseline characteristics between the no adverse events group and the adverse events group
| Basic characteristics and results | No adverse events (n = 201) | Adverse events (n = 82) | P value |
|---|---|---|---|
| Population composition and measurement | |||
| Female sex (%) | 78 (38.8%) | 18 (22.0%) | 0.008 |
| Age (Years) | 51 (43.25–60) | 49 (41.75–59.25) | 0.236 |
| Heigh (m) | 1.67 (1.60–1.73) | 1.69 (1.61–1.73) | 0.185 |
| Weight (kg) | 69.25 (60–76) | 75 (65–84) | 0.06 |
| BMI (kg/m2) | 24.53 (22.90–26.31) | 26.08 (23.41–28.35) | 0.02 |
| BSA (m2) | 1.76 (1.58–1.89) | 1.83 (1.65–1.95) | 0.025 |
| Office SBP (mmHg) | 148 (140–160) | 158 (145–170) | < 0.001 |
| Office DBP (mmHg) | 93.19 ± 12.95 | 99.9 ± 17.43 | 0.002 |
| Cardiovascular disease risk factors | |||
| Smoking history | 65 (31.90%) | 36 (43.90%) | 0.008 |
| Drinking history | 78 (38.20%) | 43 (52.40%) | 0.054 |
| Family history | 96 (47.10%) | 68 (82.90%) | 0.028 |
| LV* remodeling | 69 (33.80%) | 56 (68.30%) | < 0.001 |
| High blood glucose | 72 (35.80%) | 42 (51.20%) | 0.021 |
| Laboratory tests | |||
| Glucose (mmol/L) | 5.71 ± 1.58 | 6.16 ± 1.84 | 0.039 |
| TC (mmol/L) | 4.62 ± 1.14 | 4.72 ± 0.99 | 0.499 |
| TG (mmol/L) | 1.59 ± 0.87 | 1.90 ± 1.61 | 0.102 |
| LDL (mmol/L) | 1.59 ± 0.87 | 1.90 ± 1.61 | 0.037 |
| HDL (mmol/L) | 1.22 (1.05–1.38) | 1.15 (0.93–1.38) | 0.52 |
| 24 h ambulatory blood pressure | |||
| Average daily SBP (mmHg) | 142.32 ± 15.18 | 149.91 ± 16.92 | < 0.001 |
| Average daily DBP (mmHg) | 87.64 ± 11.21 | 92.20 ± 12.67 | 0.003 |
| Diurnal mean SBP (mmHg) | 147.09 ± 16.61 | 153.98 ± 18.50 | 0.002 |
| Diurnal mean DBP (mmHg) | 90.69 ± 12.47 | 94.85 ± 12.80 | 0.012 |
| Night mean SBP (mmHg) | 134.25 ± 13.92 | 144.32 ± 16.94 | < 0.001 |
| Night mean DBP (mmHg) | 158 (145–170) | 90 (79.75–96) | < 0.001 |
| Myocardial work related index | |||
| GLS (%) | –18 (–20 to − 17) | − 16 (− 17.5 to − 14) | < 0.001 |
| GWI (mmHg%) | 2327 (2101–2611.5) | 2079 (1824–2346) | < 0.001 |
| GCW (mmHg%) | 2610 (2295–2896) | 2321 (2068–2600) | < 0.001 |
| GWW (mmHg%) | 127 (88–186.5) | 161 (103–215.5) | 0.022 |
| GWE (%) | 94 (92–96) | 93 (91–94.5) | < 0.001 |
Data are presented as the mean ± standard deviation, number (%), or median (interquartile range)
BMI Body mass index; BSA Body surface area; DBP Diastolic blood pressure; GCW Global constructive work; GLS Global longitudinal strain; GWE Global work efficiency; GWI Global work index; GWW Global wasted work; HDL High-density lipoprotein; LDL Low-density lipoprotein; LV Left ventricular; SBP Systolic blood pressure; TC Total cholesterol; TG Triglycerides
Statistically significant at P < 0.05