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. 2023 Nov 10;15:1251075. doi: 10.3389/fnagi.2023.1251075

Table 3.

Summary of MWT in 3xTg-AD mouse model.

Difference between WT and Tg Age (months) Sex Behavior Effect sizes/significance (η2, d, p) Authors
4 M No significant differences between WT and Tg at 4 mo. p > 0.05 (4 mo.) Várkonyi et al. (2022)
8 Tg found platform slower than WT on day 5. η2 = 0.57 (8 mo.)
12, 15 M, F Tg have worse spatial learning acquisition (on day 1 and 2). η2 = 0.17 (12 mo. M) Blázquez et al. (2014)
η2 = 0.32 (12 mo. F)
η2 = 0.23 (15 mo. M)
η2 = 0.29 (15 mo. F)
13 M Tg had worse spatial learning acquisition on day 1. η2 = 0.05 Torres-Lista et al. (2015)