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. Author manuscript; available in PMC: 2023 Dec 6.
Published in final edited form as: Nat Biomed Eng. 2022 Oct 31;6(12):1353–1369. doi: 10.1038/s41551-022-00942-x

Figure 1: Representation learning for networks in biology and medicine.

Figure 1:

Given a biomedical network, a representation learning method transforms the graph to extract patterns and leverage them to produce compact vector representations that can be optimized for the downstream task. The far right panel shows a local 2-hop neighborhood around node u, illustrating how information (e.g., neural messages) can be propagated along edges in the neighborhood, transformed, and finally aggregated at node u to arrive at the u’s embedding.