Table 2.

Novel therapies for treating Pseudomonas aeruginosa infections.

Novel therapeutic agents	Mode of action/target	Reference
Quorum sensing inhibitors	Signal molecule degradation, preventing accumulation of signal molecules and antagonism of the signals	Chamomile, carrot [158], garlic [159], salicylic acid [160], furanones [161]
Immunotherapy	PcrV protein, flagellin, LPS	KB001-A [162], Immunoglobulin Y [163], Panobacumab [164]
Iron chelators	Chelation of the environmental iron	Gallium [165]
Vaccines	Polysaccharide, PcrV,OprI,Hcp1, FlgE, fructose bisphosphate aldolase, OprH gene product	PcrV-OprI-Hcp1-Trivalent vaccine [166], Polyvalent vaccine [167]
Herbal medicine	Exopolysaccharide production, phenazine pyocyanin, rhamnolipids, elastase and alkaline protease	Tanreqing [168], Herba patriniae[169]
Phage therapy	Lysis of cell membrane and wall	Pf3R [170], Genetically engineered synthetic phages [171]