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. 2023 Nov 10;39(12):btad680. doi: 10.1093/bioinformatics/btad680

Figure 1.

Figure 1.

Final prior effects γ (y-axis) against initial prior effects z (x-axis), under exponential calibration (red points on continuous curve) and isotonic calibration (blue points on discontinuous curve). The thin black line corresponds to perfect calibration (γ=β). We simulated the feature matrix X from a standard Gaussian distribution (n =200, p =500) and the initial prior effects z from a trimmed standard Gaussian distribution (trimmed below the 1% and above the 99% quantile). We set the true coefficients to (1) β=z, (2) β=sign(z)|z|, (3) β=sign(z)z2, (4) β=I[z>0]z, (5) β=I[z>1], or (6) β=I[z0]|z|+I[z>0]z2. And we simulated the response vector y from Gaussian distributions with the means η and the variance Var(η), where η=. While exponential calibration performs slightly better in the first three scenarios (top), isotonic calibration performs much better in the last three scenarios (bottom).