Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 28;165(1):bqad179. doi: 10.1210/endocr/bqad179

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)

PMC Copyright notice

Figure 5. — Sex- and age-selective effect of CBG on the liver transcriptome. A, Venn diagrams show the number of differentially expressed genes between wild-type and CBG-knockout rats in males and females at PD30 and PD60. Genes that were up- and downregulated in CBG-knockout rats compared to wild-type are listed. Genes in purple font indicate that they were differentially expressed at both PD30 and PD60. B, Volcano plot showing CBG-dependent genes in adult females (492 genes). Approximately half of these CBG-dependent genes were downregulated in females lacking CBG, and the remaining were upregulated (adjusted P value < .05). C, Gene ontology analysis revealed CBG-dependent biological processes in adult females. Numbers of DEGs belonging to each biological process are indicated. N = 4 per group. PD = postnatal day.