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. 2023 Nov 11;9(1):12–23. doi: 10.1016/j.ncrna.2023.11.006

Fig. 8.

Fig. 8

The effect of β-TRCP overexpression in HTR-8/SVneo cells with shHOXD-AS1.

β-TRCP overexpression and HOXD-AS1 knockdown was performed in HTR-8/SVneo cells. A The RNA level of HOXD-AS1, miR-135a and β-TRCP in HTR-8/SVneo cells. B The protein level of β-TRCP, IκBα, NF-κB p65, and NLRP3. C Cell activity deteced by CCK8 assay. D The level of IL-18 and IL-1β in the supernatant of HTR-8/SVneo cells. E Cell apoptosis measured by flow cytometry. F Cell invasion. G Cell migration. ns, not significant; *p < 0.05, ***p < 0.001, vs. shNC group; ###p < 0.001, vs. sh HOXD-AS1 + pcDNA4.0 group.