. 2023 Nov 19;21:5686–5697. doi: 10.1016/j.csbj.2023.11.022

Table 3.

Properties of the protein heterodimers studied. The significant length (number of sequences in cMSA / Size of both proteins) is indicated for each protein complex. As they are all lower than the required 0.7 for most DCA analysis in single proteins [23], we used our method, based on the local convolution of ECs, to reduce the number of false positives generated and highlight the most likely interacting partners [6].

	Protein size (AA)	Number of individual sequences	Number of sequences in cMSA	Sig. length	Sequence coverage
INTS9	658	223	204	0.16	55 – 90%
INTS11	600	239	204	0.16	55 – 90%
INTS4	963	202	171	0.11	55 – 90%
INTS9	658	223	171	0.11	55 – 90%
INTS4	963	202	171	0.11	55 – 90%
INTS11	600	239	171	0.11	55 – 90%
CPSF100	782	179	138	0.1	55 – 90%
CPSF73	684	161	138	0.1	55 – 90%