Table 4.
A: Multivariate logistic regression analysis results (association with severity). B: Multivariate Cox regression analysis results (association with survival).
| A | ||||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted analysis | Adjusted analysis | |||||||
| Odds Ratio | 95% CI | P-value | Adjusted odds ratio | Pr(>|z | ) | ||||
| Age | 1.033 | 1.03 | 1.04 | 1.031 | 1.09E-11 | *** | ||
| Sex | MALE | 1.092 | 0.94 | 1.27 | 2.57E-01 | 0.891 | 2.35E-01 | |
| COVID_Vaccination | Vaccinated | 0.356 | 0.29 | 0.44 | <2.00e-16 | 0.283 | <2.00e-16 | *** |
| BMI | Obese | 1.075 | 0.84 | 1.37 | 5.61E-01 | 0.801 | 1.52E-01 | |
| Overweight | 1.068 | 0.84 | 1.37 | 6.00E-01 | 1.004 | 9.78E-01 | ||
| Underweight | 2.221 | 1.31 | 3.78 | 3.25E-03 | 1.313 | 4.04E-01 | ||
| Race | Black | 1.362 | 0.66 | 2.80 | 4.02E-01 | 1.496 | 3.11E-01 | |
| Asian | 0.846 | 0.39 | 1.82 | 6.69E-01 | 1.321 | 5.16E-01 | ||
| Pacific_Islander | 0.779 | 0.37 | 1.63 | 5.08E-01 | 1.787 | 1.57E-01 | ||
| Smoking_status | Smoker | 0.858 | 0.73 | 1.02 | 7.42E-02 | 0.804 | 5.30E-02 | . |
| CCI_Level | MODERATE | 1.418 | 1.12 | 1.79 | 3.38E-03 | 1.345 | 6.03E-02 | . |
| SEVERE | 2.793 | 2.30 | 3.39 | <2.00e-16 | 1.775 | 9.34E-04 | *** | |
| ISS_staging | Moderate_Severe | 1.342 | 1.07 | 1.68 | 1.03E-02 | 1.516 | 4.14E-03 | ** |
| Medical history | Pulmonary | 2.267 | 1.92 | 2.68 | <2.00e-16 | 1.528 | 1.43E-04 | *** |
| Hypertension | 1.901 | 1.62 | 2.23 | 3.11E-15 | 0.922 | 4.93E-01 | ||
| PVD | 1.784 | 1.45 | 2.19 | 3.00E-08 | 1.030 | 8.26E-01 | ||
| Diabetes | 2.081 | 1.78 | 2.44 | <2.00e-16 | 1.060 | 6.02E-01 | ||
| Renal | 2.391 | 2.05 | 2.79 | <2.00e-16 | 1.537 | 3.25E-04 | *** | |
| Treatment | IMiDs | 1.046 | 0.87 | 1.25 | 6.28E-01 | 1.437 | 2.81E-03 | ** |
| PI | 1.000 | 0.80 | 1.26 | 9.98E-01 | 1.503 | 1.07E-02 | * | |
| BMT | 0.448 | 0.37 | 0.54 | 4.44E-16 | 0.790 | 6.68E-02 | . | |
| Daratumumab | 0.955 | 0.73 | 1.26 | 7.43E-01 | 1.090 | 6.37E-01 | ||
| Dexamethasone | 0.477 | 0.06 | 4.05 | 4.97E-01 | 2.231 | 5.78E-05 | *** | |
| B | ||||||
|---|---|---|---|---|---|---|
| Adjusted Hazards Ratio (coef) | lower 0.95 | upper 0.95 | Pr(>|z|) | |||
| Age | 1.040 | 1.02 | 1.06 | 3.98E-07 | *** | |
| Sex | MALE | 0.793 | 0.57 | 1.09 | 1.58E-01 | |
| COVID vaccination | Vaccinated | 0.302 | 0.19 | 0.47 | 1.02E-07 | *** |
| BMI | Obese | 1.045 | 0.67 | 1.64 | 8.48E-01 | |
| Overweight | 1.287 | 0.84 | 1.97 | 2.44E-01 | ||
| Underweight | 0.808 | 0.28 | 2.31 | 6.90E-01 | ||
| Race | Black | 2.630 | 0.36 | 19.21 | 3.41E-01 | |
| Asian | 2.192 | 0.27 | 17.72 | 4.62E-01 | ||
| Pacific_Islander | 2.847 | 0.38 | 21.24 | 3.08E-01 | ||
| Smoking status | Smoker | 0.918 | 0.65 | 1.30 | 6.27E-01 | |
| CCI Level | MODERATE | 3.340 | 1.68 | 6.65 | 6.05E-04 | *** |
| SEVERE | 5.138 | 2.55 | 10.36 | 4.84E-06 | *** | |
| ISS staging | Moderate_Severe | 1.549 | 0.98 | 2.45 | 6.22E-02 | . |
| Medical history | Pulmonary | 1.009 | 0.71 | 1.43 | 9.62E-01 | |
| Hypertension | 0.961 | 0.64 | 1.45 | 8.49E-01 | ||
| PVD | 1.619 | 1.12 | 2.34 | 1.05E-02 | * | |
| Diabetes | 0.737 | 0.52 | 1.04 | 8.29E-02 | . | |
| Renal | 1.080 | 0.75 | 1.55 | 6.80E-01 | ||
| Treatment | IMiDs | 1.257 | 0.87 | 1.82 | 2.28E-01 | |
| PI | 1.623 | 1.06 | 2.48 | 2.46E-02 | * | |
| BMT | 0.653 | 0.42 | 1 | 5.49E-02 | . | |
| Daratumumab | 1.291 | 0.80 | 2.09 | 2.97E-01 | ||