Table 2.
Effect of age on outcome. Results are presented as adjusted and unadjusted OR for each outcome. Age groups 40–<60, 60–<80, and >80 years old were compared to the reference group <40 years old.a
| Age Groups | ||||
|---|---|---|---|---|
| Outcome | <40 years | 40–<60 years | 60–<80 years | >80 years |
| Mortality N (%) | 41 (0.03) | 176 (0.11) | 463 (0.42) | 397 (2.04) |
| OR Unadj | Reference | 3.81 (2.71–5.35)* | 14.52 (10.55–19.99)* | 72.71 (52.70–100.32)* |
| OR Adj | Reference | 2.20 (1.56–3.10)* | 4.66 (3.35–6.47)* | 16.06 (11.48–22.45)* |
| Wound outcome N (%) | 530 (0.37) | 1,191 (0.74) | 1,719 (1.54) | 383 (1.97) |
| OR Unadj | Reference | 2.00 (1.81–2.22)* | 4.21 (3.81–4.64)* | 5.40 (4.73–6.17)* |
| OR Adj | Reference | 1.53 (1.28–1.83)* | 2.13 (1.79–2.53)* | 1.91 (1.53–2.38)* |
| Cardiac outcome N (%) | 32 (0.02) | 170 (0.11) | 512 (0.46) | 223 (1.15) |
| OR Unadj | Reference | 4.71 (3.23–6.88)* | 20.59 (14.40–29.43)* | 51.86 (35.79–75.14)* |
| OR Adj | Reference | 2.15 (1.23–3.77)** | 4.53 (2.66–7.73)* | 7.04 (4.04–12.27)* |
| Respiratory outcome N (%) | 337 (0.24) | 786 (0.49) | 1,587 (1.42) | 642 (3.31) |
| OR Unadj | Reference | 2.07 (1.82–2.36)* | 6.11 (5.43–6.87)* | 14.46 (12.66–16.51)* |
| OR Adj | Reference | 1.13 (1.15–1.78)** | 2.02 (1.64–2.48)* | 2.27 (1.81–2.86)* |
| Urinary outcome N (%) | 54 (0.04) | 223 (0.14) | 449 (0.40) | 153 (0.79) |
| OR Unadj | Reference | 3.67 (2.72–4.93)* | 10.69 (8.06–14.18)* | 21.01 (15.40–28.66)* |
| OR Adj | Reference | 2.79 (1.77–4.41)* | 2.77 (1.76–4.35)* | 2.56 (1.57–4.19)** |
| CNS outcome N (%) | 11 (0.01) | 36 (0.02) | 105 (0.09) | 78 (0.40) |
| OR Unadj | Reference | 2.90 (1.48–5.70)** | 12.24 (6.58–22.78)* | 52.38 (27.86–98.49)* |
| OR Adj | Reference | 1.80 (0.65–4.99) | 5.36 (2.11–13.65)** | 13.62 (5.23–35.50)* |
| Thromboembolism N (%) | 196 (0.14) | 358 (0.22) | 477 (0.43) | 156 (0.80) |
| OR Unadj | Reference | 1.62 (1.36–1.93)* | 3.13 (2.65–3.69)* | 5.90 (4.78–7.28)* |
| OR Adj | Reference | 1.35 (0.99–1.84) | 1.82 (1.35–2.45)* | 2.30 (1.62–3.27)* |
| Sepsis N (%) | 476 (0.33) | 1,201 (0.75) | 2,170 (1.95) | 719 (3.70) |
| OR Unadj | Reference | 2.25 (2.02–2.50)* | 5.94 (5.37–6.56)* | 11.50 (10.235–12.93)* |
| OR Adj | Reference | 1.72 (1.45–2.05)* | 2.39 (2.02–2.82)* | 2.28 (1.88–2.77)* |
| Return to OR N (%) | 979 (0.69) | 1,391 (0.86) | 1,629 (1.46) | 371 (1.91) |
| OR Unadj | Reference | 1.26 (1.16–1.37)* | 2.15 (1.98–2.33)* | 2.82 (2.50–3.19)* |
| OR Adj | Reference | 1.12 (0.96–1.30) | 1.36 (1.16–1.58)* | 1.21 (0.99–1.19) |
| Composite morbidity N (%) | 1,330 (0.93) | 3,039 (1.89) | 5,096 (4.457) | 1,708 (8.79) |
| OR Unadj | Reference | 2.05 (1.92–2.18)* | 5.10 (4.80–5.42)* | 10.26 (9.54–11.05)* |
| OR Adj | Reference | 1.54 (1.38–1.72)* | 2.11 (1.89–2.35)* | 2.35 (2.07–2.67)* |
a
Variables considered and adjusted in the multivariate analysis were: underlying medical conditions [congestive heart failure within 30 days prior to surgery, severe COPD, acute renal failure (pre-operative), bleeding disorders, cancer, ascites within 30 days prior to surgery], preoperative treatments (dialysis, ventilation, chemotherapy, radiation therapy, and ASA classification.
*
p < 0.0001.
**
p < 0.05.