Table 1.
NFAT member | Alternative name(s) | Number of variants | Regulated by | CNS distribution |
---|---|---|---|---|
NFAT1 | NFATc2 and NFATp | 8 | Ca2+/Calcineurin | oflactory bulb, neuronal cell line |
NFAT2 | NFATc1 and NFATc | 8 | Ca2+/Calcineurin | hypothalamus, hippocampus, cerebellum, olfactory bulb, and frontal cortex |
NFAT3 | NFATc4 | 24 | Ca2+/Calcineurin | olfactory bulb, cerebellum, and certain regions of the cortex |
NFAT4 | NFATc3 and NFATx | 6 | Ca2+/Calcineurin | hippocampus, retinal ganglion cells |
NFAT5 | TonEBP and OREBP | 16 | Osmotic stress | cerebral cortex, hippocampus, hypothalamus, substantia nigra, cerebellum, medulla oblongata |