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. 2023 Nov 23;14:1281882. doi: 10.3389/fimmu.2023.1281882

Table 1.

General features of NFAT family members and their distribution in the brain.

NFAT member Alternative name(s) Number of variants Regulated by CNS distribution
NFAT1 NFATc2 and NFATp 8 Ca2+/Calcineurin oflactory bulb, neuronal cell line
NFAT2 NFATc1 and NFATc 8 Ca2+/Calcineurin hypothalamus, hippocampus, cerebellum, olfactory bulb, and frontal cortex
NFAT3 NFATc4 24 Ca2+/Calcineurin olfactory bulb, cerebellum, and certain regions of the cortex
NFAT4 NFATc3 and NFATx 6 Ca2+/Calcineurin hippocampus, retinal ganglion cells
NFAT5 TonEBP and OREBP 16 Osmotic stress cerebral cortex, hippocampus, hypothalamus, substantia nigra, cerebellum, medulla oblongata