Table 1.

Datasets size of EnzymeNet.

Step	Type	EC	Training	Validation	Test
First prediction		EC 1	180 177	22 160	22 161
		EC 2	279 647	34 487	34 473
	Positive	EC 3	206 177	25 408	25 418
		EC 4	81 624	10 057	10 054
		EC 5	50 103	6180	6182
		EC 6	44 521	5489	5489
		Non-enzyme	113 881	14 225	14 272
	Negative	Random substitution	13 585	1695	1684
		Consecutive substitution	13 580	1710	1674
Second prediction		EC 1 fourth digit	122 858	14 961	14 961
		EC 2 fourth digit	284 539	35 139	35 139
	Positive	EC 3 fourth digit	222 466	27 511	27 511
		EC 4 fourth digit	658,52	8065	8065
		EC 5 fourth digit	55 187	6825	6825
		EC 6 fourth digit	107 511	13 380	13 380