Table 2.
Comparison of key features of Tri©DB with those of other similar resources
| Database | Release time | Key knowledge domain | Primary presentation | Graphical presentation | Meta data | Pathway/interaction | Germline mutations | Immuno therapy | Cell therapy | Data access | Annotation report |
|---|---|---|---|---|---|---|---|---|---|---|---|
| oncoKB | 2017 | Gene alterations, Therapies, Diseases, Brief interpretations | Tables, Texts | Lollipop graphs, Barcharts | Functional annotations, Population frequencies, Functional domains, Drug resistance | No | No | Yes | No |
Browse, Search, API |
Yes, license needed |
| CIViC | 2017 | Gene alterations, Therapies, Diseases, Clinical trials, Assertive interpretations | Tables, Texts | / | Functional annotations, Population frequencies, Drug resistance, Literature references | No | No | Yes | No |
Browse, Search, API, Download |
No |
| MCG | 2011 | Gene alterations, Therapies, Diseases, Clinical trials, Brief interpretations |
Forms, Texts |
Barchats, Pathway maps | Functional annotations, Population frequencies, Literature references | Yes | No | Yes | No | Browse, Search | No |
| PMKB | 2017 | Gene alterations, Therapies, Diseases, Interpretations |
Forms, Texts |
/ |
Functional annotations, Drug resistance, External cross-links |
No | No | No | No |
Browse, Search, API |
No |
| CGI | 2018 | Gene alterations, Therapies, Diseases | Tables, Texts | / | Functional annotations, Drug resistance, External cross-links | No | No | No | No | Annotate, Filter, API, Download | No |
| JAX-CKB | 2016 |
Gene alterations, Therapies, Diseases, Clinical trials, Interpretations |
Tables, Forms, Texts |
/ | Functional annotations, Drug resistance, External cross-links, Literature references | No | Not explicit | Yes | No | Partial access, license needed | No |
| Tri©DB | 2022 |
Gene alterations, Therapies, Diseases, Clinical trials, Recapitulative interpretations |
Tables, Forms, Texts |
Pathway maps, Interaction networks, Lollipop graphs, Barcharts | Functional annotations, Population frequencies, Functional domains, Drug resistance, Molecular structures, External cross-links, Literature references | Yes | Yes | Yes | Yes |
Browse, Search, API, Download |
Yes |