Table 1.
Demographics and neuropsychological assessment of SCD and MCI subjects.
| SCD (n = 14) | MCI (n = 16) | |||||
|---|---|---|---|---|---|---|
| T0 | T2 | p | T0 | T2 | p | |
| Age | 67.21 ± 6.90 | 67.21 ± 6.90 | – | 65.94 ± 7.03 | 65.94 ± 7.03 | – |
| Female | 11 | 11 | – | 14 | 14 | – |
| Education | 11.75 ± 2.94 | 11.75 ± 2.94 | – | 12.5 ± 2.76 | 12.5 ± 2.76 | – |
| MMSE | 28.29 ± 1.44 | 28.43 ± 1.29 | 0.655 | 27.69 ± 1.40 | 28.13 ± 1.17 | 0.387 |
| MOCA | 25.57 ± 1.84 | 25.79 ± 2.40 | 0.732 | 23.88 ± 2.23 | 24.81 ± 3.68 | 0.243 |
| CDR | 0.43 ± 0.18 | 0.36 ± 0.23 | 0.1665 | 0.38 ± 0.22 | 0.28 ± 0.26 | 0.333 |
| AVLT-20-min DR | 5.71 ± 2.68 | 7.29 ± 2.60 | 0.049* | 4.56 ± 3.00 | 7.25 ± 2.63 | 0.001* |
| LMT-20-min DR | 3.86 ± 2.61 | 5.79 ± 3.95 | 0.182 | 4.00 ± 2.87 | 5.25 ± 2.63 | 0.159 |
| CFT-20-min DR | 18.79 ± 4.23 | 20.07 ± 6.43 | 0.450 | 10.44 ± 6.37 | 18.19 ± 7.38 | 0.001** |
| VFT | 20.5 ± 3.64 | 21.64 ± 4.42 | 0.411 | 25.19 ± 28.08 | 18.19 ± 2.94 | 0.373 |
| DST-backward | 12.79 ± 1.37 | 13.43 ± 3.20 | 0.456 | 11.25 ± 1.30 | 12.13 ± 1.65 | 0.074 |
| DSST | 39.8 ± 10.19 | 43.21 ± 14.19 | 0.186 | 32.44 ± 6.37 | 38.06 ± 9.74 | 0.032* |
| TMT-A | 52.64 ± 10.74 | 56.43 ± 16.71 | 0.321 | 64.06 ± 18.71 | 58.06 ± 13.80 | 0.074 |
| CFT | 35.36 ± 1.59 | 35.36 ± 1.11 | 1.000 | 32.56 ± 3.94 | 34.25 ± 1.92 | 0.041* |
| CDT | 9.29 ± 0.96 | 9.07 ± 0.70 | 0.385 | 9.13 ± 0.93 | 9.25 ± 0.66 | 0.652 |
| HAMD | 4.36 ± 4.05 | 3.14 ± 3.81 | 0.405 | 3.44 ± 2.34 | 12.00 ± 1.73 | 0.012* |
| HAMA | 5.43 ± 6.04 | 4.71 ± 4.60 | 0.609 | 4.00 ± 2.03 | 1.75 ± 1.35 | 0.002* |
| SCD-Q | 6.29 ± 0.84 | 6.07 ± 1.10 | 0.481 | 5.72 ± 1.29 | 5.38 ± 1.52 | 0.127 |
Numbers are given as means (standard deviation, SD) unless stated otherwise. Paired t-tests were used to test for statistical differences between groups before and after the TMS intervention. *showed a significantly group difference between T0 and T2, p < 0.05; SCD, subjective cognitive decline; MCI, mild cognitive impairment.